Table 3.
Desferrithiocin Analogue | Non-Renal Perfusion Protocol | Renal Perfusion Protocol | |
---|---|---|---|
10-d | 384 µmol/kg/d poa,b | 237 µmol/kg b.i.d. × 7 dc,d | |
30-d | Iron-loaded (350 mg Fe/kg) | 474 µmol/kg s.i.d. × 7 da | |
119 µmol/kg/d pod,e | |||
10-d | 384 µmol/kg/d pod,e | 237 µmol/kg b.i.d. × 7 dd,e | |
30-d | Unloaded only | ||
63.3 µmol/kg/d pod,e | |||
10-d | 384 µmiol/kg/d pod,e | ||
28-d | Iron-loaded (350 mg Fe/kg) | ||
75 µmol/kg poe | |||
150 µmol/kg poe | 237 µmol/kg b.i.d. × 7 de | ||
300 µmol/kg poe | |||
28-d | Unloaded | ||
75 µmol/kg poe | |||
150 µmol/kg poe | |||
300 µmol/kg poe |