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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Neuropeptides. 2009 Jun 21;43(4):283–293. doi: 10.1016/j.npep.2009.05.006

Table 1.

Effects of insulin on the single cell unit activity of cerebellar neurons.

Electrophysiological effects Number of neurons tested Number of significant neuronal responses Number and percent of neurons showing significant effects
Effects of control drugs:
1. GABA inhibition 46 285 46/46 (100%)
2. Glutamate excitation 5 21 5/5 (100%)
GABA-dependent effects of insulin:
1. GABA-dependent insulin inhibition 47 148 29/47 (62%)
2. HNMPA blocks GABA-dependent insulin inhibition 13 35 13/13 (100%)
3. Insulin decreases GABA inhibition 47 59 18/47 (38%)
GABA-independent effects of insulin:
1. GABA-independent insulin excitation 47 15 3/47 (6%)
Total number of neurons / microiontophoretic trials 47 563