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. 2009 Nov;50(11):2235–2244. doi: 10.1194/jlr.M900036-JLR200

TABLE 1.

Influence of scavenger receptors on intestinal cholesterol absorption in mice fed a basal dieta

24 h Absorption Efficiency (%)
4 h Intestinal Content (% Initial Dose)
% Initial Dose in 100 μl Plasma at 4 h
% Initial Dose in 100 mg Liver at 4 h
Mouse Genotype (n = 7/group) (n = 8/group) (n = 8/group) (n = 8/group)
WT 70 ± 11 40 ± 7 0.13 ± 0.06 0.92 ± 0.14
SR-BI−/− 66 ± 14 40 ± 6 0.18 ± 0.09 0.88 ± 0.53
CD36−/− 65 ± 8 31 ± 11 0.08 ± 0.04 0.43 ± 0.22
SR-BI−/−/CD36−/− 67 ± 13 34 ± 12 0.18 ± 0.10 0.67 ± 0.48

All values are mean ± SD. No significant differences between mouse genotypes were evident by ANOVA.

a

The mice weighed 26.4 ± 2.8 g and were aged 3–5 months.