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. Author manuscript; available in PMC: 2009 Oct 10.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2009 Mar 25;50(9):4162–4172. doi: 10.1167/iovs.08-2861

TABLE 3.

Genes for Which SP/nSP or nSP/SP SI Ratios Are Larger Than 10

Gene Symbol SP-SI SP/nSP Annotations
A. SP > nSP

    E-selectin/CD62E/ELAM 1 SELE 1260 141.81 Heterologous cell adhesion
    Splicing factor, arginine/serine-rich 3 SFRS3 511 27.11 pre-mRNA splicing factor
    CD93 CD93 264 23.17 Heterologous cell adhesion
    E74-like-3 ELF3 3683 17.26 Epithelial nuclear transcription factor
    Potassium voltage-gated channel, Isk-rel., 3 KCNE3 857 14.95 Regulation of K_ channel
    Chemokine (C-X-C motif) receptor 4 CXCR4 367 14.51 Growth and motility receptor
    Zinc finger and BTB domain containing 10 ZBTB10 618 14.20 Nuclear transcription factor
    Heterogeneous nuclear ribonucleoprot. D HNRPD 369 13.79 pre-mRNA processing and stabilization
    Prot. phosphatase 1D mag.-dep., delta iso. PPM1D 677 12.94 Regulation of p53 induced apoptosis (stem)
    Methyltransferase-like 7A METTL7 816 12.77 Methyl transferase precursor
    Annexin A1 ANXA1 525 12.55 PLA-2 inhibitor-Inflammation inhib.
    Cytochrome P450, family 1 A, pol 1 CYP1A1 275 12.36 Xenobiotic aromatic processing
    Histone Cluster 1, H4h HIST1H 689 11.99 Histone
    Statherin STATH 1288 11.97 Secreted salivary protein
    Myosin regulatory light chain interacting protein MYLIP 1240 11.59 Inhibitor of cell motility (neurites)
    Zinc finger protein 750 ZNF750 365 11.21 Nuclear transcription factor
    Colony stimulating factor 2 receptor, beta CSF2RB 102 11.07 Granulocyte-macrophage growth receptor
    Histone cluster 1, H2bg HIST1H 284 10.86 Histone
    MAP kinase kinase kinase 8 MAP3K 1478 10.81 MAPK pathway mediator
    Dual specificity phosphatase 5 DUSP5 4262 10.61 Dephosphorylation of ERK
    Cytochrome P450, family 26-A polypeptide 1 CYP26A1 1194 10.48 Retinoic acid processing

B. nSP > SP

    Collagen, type XVII, alpha 1 COL17A1 302 31.79 Cell-matrix adhesion
    Transgelin TAGLN 1308 25.1 Cytoskeleton organization
    Parathyroid hormone-like hormone PTHLH 1036 20.13 Differentiation (mammary gland)
    Podoplanin PDPN 1352 18.56 Phyllopodia-dependent cell motility
    Dickkopf 3 DKK3 1172 16.35 Negative regulation WNT signaling
    Caldesmon 1 CALD1 5025 12.74 Cell motility
    Secretogranin V SCG5 576 12.4 Secreted protein-unknown function
    Dystonin DST 1804 11.98 Cytoskeleton organization
    Matrix metallopeptidase 9 MMP9 2090 11.27 Peptido-glycan digestion
    TGFbeta 1 induced transcript 1 TGFB111 355 11.2 Focal adhesion adapter
    Interleukin 13 receptor, alpha 2 IL13RA2 11453 10.14 Interleukin receptor