Table 2.

Observed mean value ± standard error and mean values of the % predicted ± standard error for the pulmonary function test variables for sex, smoking status and TLR4 Asp299Gly

	Sex		Smoking Status#		TLR4 299#
	Male (n = 754)	Female (n = 971)	Never Smoker (n = 937)	Ever Smoker (n = 788)	Wild type (n = 1490)	Polymorphic (n = 235)
Observed FEV1(L)	3.78 ± 0.03	2.65 ± 0.02	3.21 ± 0.03	3.18 ± 0.03	3.18 ± 0.02	3.31 ± 0.06+
% predicted	98.44 ± 0.59	102.86 ± 0.54	102.47 ± 0.53	99.09 ± 0.60&	100.91 ± 0.43	101.01 ± 1.05
Observed FVC (L)	4.73 ± 0.04	3.39 ± 0.02	3.97 ± 0.04	3.98 ± 0.04	3.95 ± 0.03	4.14 ± 0.07+
% predicted	98.55 ± 0.55	103.24 ± 0.51	102.38 ± 0.50	99.77 ± 0.57&	101.10 ± 0.41	101.76 ± 0.97
Observed FEV1/FVC	0.80 ± 0.002	0.81 ± 0.002	0.81 ± 0.0.002	0.80 ± 0.0.002&	0.80 ± 0.002	0.80 ± 0.004
% predicted	99.96 ± 0.29	100.06 ± 0.25	100.39 ± 0.26	99.57 ± 0.27&	100.11 ± 0.20	99.44 ± 0.49
Observed FEF25-75(L/s)	3.82 ± 0.05	2.89 ± 0.03	3.36 ± 0.04	3.21 ± 0.04&	3.28 ± 0.03	3.37 ± 0.08
% predicted	101.28 ± 1.10	103.89 ± 1.06	105.64 ± 1.04	99.30 ± 1.13&	102.89 ± 0.82	101.80 ± 2.17

Note: Predicted values are adjusted for age and height.

* Comparison made between Male and Female p value < 0.05

** Comparison made between Male and Female p value < 0.10

⁺ Comparison made between wild type and polymorphic group p value < 0.05

^&Comparison made between never smoker and ever smoker group p value < 0.05

^# Separate prediction equations used for males and females.