Table 1.
Effects of bupivacaine microspheres and RTX on nociception, motor function, and proprioception.
Hop | Flip | Pinch (sural) | Pinch (saphenous) | |||||
Normal | Blocked | Normal | Blocked | Normal | Blocked | Normal | Blocked | |
Control (n = 6) | 6 | 0 | 6 | 0 | 6 | 0 | 6 | 0 |
RTX only (n = 5) | 5 | 0 | 5 | 0 | 5 | 0 | 5 | 0 |
Bub only (n = 3) | 0 | 3 | 0 | 3 | 0 | 3 | 3 | 0 |
SNI+vehicle (n = 10) | 0 | 10 | 0 | 10 | 10 | 0 | 10 | 0 |
SNI+RTX (n = 9) | 0 | 9 | 0 | 9 | 9 | 0 | 9 | 0 |
SNI+Bup (n = 5) | 0 | 5 | 0 | 5 | 0 | 5 | 5 | 0 |
Nociceptive response was tested by pinching the hind paws in the sural and saphenous nerve territories. Proprioception and motor function were examined by checking hopping and flipping responses.