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. 2009 Sep 22;5:55. doi: 10.1186/1744-8069-5-55

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Copyright © 2009 Zhao et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Showing a comparison of long-term potentiation (LTP) of field excitatory postsynaptic potential (fEPSP) in the hippocampal formation induced by perforant path theta burst stimulation (TBS) conditioning between groups of rats in naïve, saline (Sal-control), bee venom (BV)-inflamed and peripheral impulse blockade state. The amplitude (A, B) and slope (C, D) of both dentate gyrus (A, C) and CA1 (B, D) fEPSP were normalized as percentage of the pre-TBS baseline and plotted as a function of time. Enhancement of network LTP by BV-induced persistent nociception could be reversed by local pre-blockade of nerve impulses from injury site. The number of slices used to plot the graph is indicated in parentheses. *P < 0.05 vs. naïve control; †P < 0.05 vs. saline control. Error bars: ± S.E.M.