Table 3.

Bootstrap analysis results for two-component regulatory subnetworks

# dimers binding	% of total models	% with multiple equilibria ruled out
0	0.8	26.2 [19.0, 34.4]
1	4.8	19.8 [17.1, 22.9]
2	14.5	12.6 [11.3, 14.1]
3	25.5	8.9 [8.1, 9.9]
4	28.8	4.1 [3.5, 4.7]
5	19.1	1.4 [1.0, 1.9]
6	6.5	0.0

The percentage of two-component subnetworks for which multiple equilibria can be ruled out, based on INJ analysis of ~15,000 randomly selected subnetworks (see text). Results are grouped according to the number of dimer-binding reactions in each subnetwork. Brackets indicate bootstrap 95% confidence intervals calculated by sampling with replacement 10,000 times. Overall, the capacity for multiple equilibria is ruled out by the INJ method for 6.71% [6.31%, 7.11%] of sampled subnetworks.