Table 2.
Top 10 survival-associated expression levels in CEU grandparents
| HG-focus probeset | Gene symbol | Z | P-value | H2 | Spouse correlation |
|---|---|---|---|---|---|
| HF7873 | CORO1A | −4.20 | 2.64E−05 | 0.66 | 0.23 |
| HF8664 | IQGAP1 | −3.60 | 3.19E−04 | 0.59 | 0.22 |
| HF6054 | AURKB | −3.58 | 3.41E−04 | 0.34 | −0.04 |
| HF7038 | TERF2IP | 3.37 | 7.45E−04 | 0.064 | 0.0089 |
| HF6482 | CBX5 | −3.37 | 7.46E−04 | 0.41 | −0.058 |
| HF8349 | KIF2C | −3.35 | 8.02E−04 | 0.046 | 0.035 |
| HF657 | ACTR2 | −3.27 | 1.07E−03 | 0.45 | 0.068 |
| HF2735 | SPAG5 | −3.21 | 1.31E−03 | 0.39 | −0.012 |
| HF2854 | MTF2 | −3.17 | 1.54E−03 | 0.25 | 0.040 |
| HF7574 | EMP3 | −3.13 | 1.74E−03 | 0.068 | −0.0026 |
Probeset, probeset name from HG-focus refseq transcript library [see reference (Liu et al., 2007)]; gene symbol(s), HUGO symbol name or names corresponding to current mapping of probeset sequence; Z, Z-score from proportional hazards model of survival vs. age-adjusted expression; P-value, probability of observing a Z greater than that observed; H2, heritability.