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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Cancer Res. 2009 Sep 29;69(19):7644–7652. doi: 10.1158/0008-5472.CAN-09-0823

Figure 5. Effect of BEZ235 and IR in a xenograft tumor model.

Figure 5

A. Xenograft growth of H460 cells in nude mice treated as indicated. The graph shows xenograft volumes. Each point represents the mean of tumor volume (mm3) of each treatment group (n = 7); bars, SEM; ***P<0.001 between mice treated with IR to mice treated with IR+BEZ235. Mice were sacrificed when tumor volume reached 2000 mm3. B. Kaplan-Meyer curve of H460 xenografts treated as indicated. ***P<0.001 between all survival curves C. Representative pictures of mice 50 days after initiation of treatment.