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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Clin Cancer Res. 2009 Sep 29;15(19):5974–5984. doi: 10.1158/1078-0432.CCR-09-1352

Figure 5. H-89 modulates expression of genes previously implicated in the malignant phenotype of HNSCC.

Figure 5

UMSCC cells were treated with 20 μM H-89 for varying durations as shown and RNA extracted and reverse transcribed. Quantitative RT-PCR expression levels for all genes illustrated here were normalized to no treatment controls and expressed on a log scale. Each value is representative of three independent observations. (p values shown on the graphs represent the significance of highest knockdown achieved during the time points measured compared to no treatment controls.)