Table 4.
Model parameters of Equation 3 describing myofilament mechanical properties and crossbridge kinetics measured by sinusoidal length perturbation analysis. Values reported as mean ± sem.
| TG40 | NTG40 | TG15 | NTG15 | |
|---|---|---|---|---|
| A (mN.mm-2) | 267±28 | 289±32 | 235±19 | 259±12 |
| k (no units) | 0.243±0.024 | 0.208±0.017 | 0.165±0.010 | 0.152±0.008 |
| B (mN.mm-2) | 2994±806 | 4769±696 | 846±98 | 792±236 |
| b (Hz) | 1.33±0.12** | 0.84±0.09 | 1.03±0.10 | 0.78±0.11 |
| C (mN.mm-2) | 3452±864 | 5159±777 | 932±92 | 884±245 |
| c (Hz) | 1.77±0.20** | 0.99±0.10 | 1.89±0.25 | 1.58±0.13 |
| ton (ms) | 102.3±14.2** | 175.7±19.7 | 97.7±12.9 | 105.0±7.7 |
**
= significantly different from respective NTG (P<0.01).
A = magnitude of viscoelastic stiffness of passive elements; k = relative degree of viscous (k→1) versus elastic (k→0) quality of passive elements; B = magnitude of work-generating process of crossbridges; b = characteristic frequency of work generation; C = magnitude of work-absorbing process of crossbridges; c = characteristic frequency of work absorption; ton = mean crossbridge attachment time during a crossbridge cycle.