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. Author manuscript; available in PMC: 2010 Oct 14.
Published in final edited form as: J Am Chem Soc. 2009 Oct 14;131(40):14473–14479. doi: 10.1021/ja9056079

Table 1.

Antibacterial Activity of C12- and C14-TA

Bacteria C12-TA EC50, μg/mL (μM) C12-TA MIC, μg/mL C14-TA MIC, μg/mL
Gram-positive
    B. anthracis Ames strain n.d. 54 n.d.
    B. cereus PCI 213 2.4 (8.3) 12.5 3.12
    B. subtilis Marburg n.d. 25 3.12
    C. diphtheriae 48255 8.9 (30.1) 25 6.25
    E. faecalis NCTC 775 10.0 (33.7) 50 6.25
    L. plantarum NCIMB 8826 n.d. 25 12.5
    M. tuberculosis H37Rv 0.71 (2.38) 5 2.5
    S. aureus USA-300 n.d. 25 6.25
    S. aureus Wood 46 8.0 (26.7) 25 6.25
Gram-negative
    B. cepacia UCB 717 >30 (>100) n.d. n.d.
    E. coli K12 >30 (>100) n.d. n.d.
    E. coli D22 10.7 (35.9) 50 25
    E. coli Δimp 5.7 (19.2) 25 12.5
    H. influenzae AMC 36-A-1 23.4 (78.5) n.d. n.d.
    P. aeruginosa PAO-1 >30 (>100) n.d. n.d.
    V. cholerae N16961 11.2 (37.7) >100 >100
    V. cholerae TP 9.1 (30.4) 100 100
    V. harveyi BB120 21.6 (72.6) 100 6.25

n.d. = not determined