. Author manuscript; available in PMC: 2010 Oct 14.

Published in final edited form as: J Am Chem Soc. 2009 Oct 14;131(40):14473–14479. doi: 10.1021/ja9056079

Table 2.

Activity of C₁₂-TA in Gram-positive bacteria. All EC₅₀ values are reported in μM.

Bacteria	Death	ΔpH	Δψ	Membrane Permeation
B. cereus PCI 213	53.6±3.7	61.6±8.7	49.0±2.0	293±48.0
B. subtilis Marburg	64.5±1.9	60.3±16.2	23.9±5.1	110±12.6
E. faecalis NCTC 775	116±26.2	17.5±2.8	121±6.3	~875^a
S. aureus Wood 46	294±33.5	15.0±3.0	186±6.2	~575^a

Insufficient data to calculate an accurate EC₅₀