Figure 1.
Snf1 regulates UV-induced transcription. (A) Genes affected by UV irradiation in WT cells. Microarray analysis was carried out in duplicate, and genes with a significant change (false discovery rate <0.05) at the indicated time point after irradiation with 100 J/m2 of UV light were counted. (B) Two-dimensional hierarchical clustering of log-transformed fold change (FC) in gene expression between snf1Δ and WT cells at the indicated time point after irradiation. All 1903 UV-responsive genes were clustered. (C) Average UV response of all genes in Cluster 1 or 2 from panel B separated by UV activation or repression. Values are the average log-transformed FC of all genes in each category when comparing WT or snf1Δ cells after damage with the congenic undamaged cells.