Table 1. Hybrid female viability from crosses between different D. simulans and D. melanogaster strains.
| Cross (D. simulans female×D. melanogaster male) | n Hybrid Progeny | Percent Hybrid Females | |
| Males | Females | ||
| white501 (SA32)×Canton S | 232 | 13 | 5.3 |
| C167.4×Canton S | 525 | 39 | 6.9 |
| C167.4 (tet)×Canton Sa | 233 | 34 | 12.7 |
| C167.4×Oregon R | 310 | 43 | 12.2 |
| NC48S×Canton S | 180 | 0 | 0 |
| NC48S×Zhr 1 | 325 | 392 | 54.7 |
| NC48S×Zhr 1/Zhr + Y | 48 | 112 | 70.0 |
a
The C167.4 line was found to be infected with Wolbachia bacteria. This line was treated with antibiotics to produce the C167.4 (tet) line, which is cured of Wolbachia. Interspecific crosses with this line showed that Wolbachia do not influence hybrid female lethality.