Table 1.
Blood pressures, food intakes, body and organ weights of rat groups.
| Parameters | LZR-RD | LZR-HFD | LZR-RD-PDTC | LZR-HFD-PDTC | OZR-RD | OZR-HFD | OZR-RD-PDTC | OZR-HFD-PDTC |
|---|---|---|---|---|---|---|---|---|
| SBP (mmHg) | 123.2 ± 3.3 | 125.2 ± 2.1 | 122.2 ± 4.1 | 119.1 ± 3.2 | 142.3 ± 4.2 | 158.6 ± 6.6* | 140.6 ± 4.8 | 133.1 ± 5.1‡ |
| MAP (mmHg) | 101.1 ± 4.1 | 102.4 ± 3.1 | 102.1 ± 2.6 | 99.1 ± 1.4 | 126.1 ± 5.4 | 130.8 ± 5.4* | 125.6 ± 4.1 | 108.2 ± 6.1‡ |
| Body weight (g) | 377 ± 2.24 | 400.5 ± 2.6§ | 281.60 ± 7.0 | 349.3± 2.6¶ | 544.8 ± 2.04 | 397.20 ± 12.6 | 615.60 ±7.92 | 551.0 ± 2.3‡ |
| Food intake (g) | 22.7±0.48 | 20.6±0.9 | 20.80 ± 1.18 | 19.75 ± 0.93 | 23.8 ± 1.1 | 18.5 ± 0.94* | 24.00 ± 0.80 | 16.5 ± 0.7‡ |
| Kidney (g) | 1.18±0.03 | 1.28±0.04 | 1.24 ± 0.02 | 1.17±0.01 | 1.47 ± 0.08 | 1.46±0.04* | 1.47 ± 0.03 | 1.40±0.04 |
| Liver (g) | 11.19±0.18 | 14.34±0.53§ | 11.67 ± 0.29 | 11.04±0.04¶ | 18.49 ± 0.83 | 24.3±0.98* | 19.66 ± 0.85 | 23.75±1.01 |
| Abdominal fat (g) |
2.5±0.16 | 16.55±0.93§ | 4.39 ± 0.33 | 5.08±0.80¶ | 19.10 ± 0.53 | 36.86±1.53* | 28.88 ± 0.84 | 32.49±0.82‡ |
| Weight gain (g) | 179.2 ± 5.4 | 282.3 ± 3.8§ | 122.40 ± 4.1 | 226 ± 2.7¶ | 381.2 ± 10.1 | 460.3 ± 11.3* | 179.20 ± 10.8 | 391 ± 7.1‡ |
The parameters of 15 week old rats were compared. Values are expressed as means ±S.E.M. Statistical analysis was performed using one way ANOVA with repeated measurements. Post hoc pairwise mean comparisons of each treatment group to its respective control were conducted with Dunnett's test. P ≤ 0.05 were considered significant.
§
p < 0.05 LZR-RD Vs LZR-HFD,
¶
p < 0.05 LZR-HFD Vs LZR- HFD-PDTC,
*
p<0.05 OZR-RD vs. OZR-HFD;
‡
p<0.05 OZR-HFD vs. OZR-HF-PDTC.