The transcript levels of the different hypoxia markers were quantified in all participants using absolute quantitative real time RT-PCR and normalised to the expression of three placental housekeeping genes. A. The transcription profiles were similar between controls (open bars, n=24), malaria cases without intervillositis (light grey bars, n=14) and malaria complicated by intervillositis (dark grey bars, n=21). B. No difference in transcription profiles was found when comparing participants with normal birth weight (NBW, open bars, n=52) and patients with LBW (grey bars, n=7). P>.05 Mann-Whitney’s test. Bars represent median, 25th and 75th percentiles and the whiskers are 5th and 95th percentiles. Flt-1: VEGF receptor 1; HIF: Hypoxia-inducible factor; PlGF: Placental growth factor; VEGF: Vascular endothelial growth factor; sFlt-1: soluble Flt-1; Intervill.: intervillositis.