Figure 3.

Biological functions associated with disordered (DPs + MXPs) and folded/ordered proteins (FPs) in TS dataset. Graphical representation of over- and under-representation of GO terms for disordered proteins (DPs + MXPs) and folded ordered proteins (FPs) for three functional categories, (A) cell component, (B) biological process, and (C) molecular function. Results are shown only for over- and under-represent GO terms with false discover rate (FDR) values <0.01 and with ≥10 associated proteins. The column labeled Background indicates the percentage of all theoretical mouse proteins that exhibited a particular GO term using a gray scale. The columns labeled (DPs + MXPs) and FPs indicate the extent of over- (red scale) or under-representation (green scale) of a particular GO term, given as [(LH/LT) – (BH/BT)]/(BH/BT) × 100; where: LH is the number of disordered or folded proteins associated with a particular GO term, LT is the total number of disordered or folded proteins with any GO term, BH is the number of theoretical mouse proteins associated with a particular GO term, and BT is the number of theoretical mouse proteins associated with any GO term. The color and gray scales are defined in the lower right. Gray boxes in the columns labeled (DPs + MXPs) and FPs indicate that the noted GO term was not over- or under-represented for the indicated structural class and have the same shade as the box labeled Background; asterisks in the columns labeled (DPs + MXPs) and FPs indicate that zero proteins in the indicated structural class were associated with the noted GO term.