Figure 4. Relationship between serum calcium and PTH levels in wild-type and TgPTHp–Gqloop transgenic mice.
(a) Regression analysis showing the normal relationship between serum calcium and PTH levels in wild-type mice. (b) Overexpression of the Gαqloop transgene to the parathyroid gland alters the slope of the serum calcium and PTH-level relationship, consistent with impaired calcium sensing.