. Author manuscript; available in PMC: 2009 Oct 12.

Published in final edited form as: Kidney Int. 2008 Aug 27;74(12):1548–1556. doi: 10.1038/ki.2008.411

Table 1.

Comparison of serum PTH, calcium, and phosphorus in wild-type and Tg^{PTHp–Gqloop} transgenic mice, wild-type and Gαq^+/− heterozygous mice, and wild-type and CASR^+/− heterozygous mice

	Serum
	PTH (pg/ml)	Calcium (mg/100 ml)	Phosphorus (mg/100 ml)
WT	25.426 ± 2.478	9.142 ± 0.201	6.433 ± 0.445
Tg^{PTHp–Gqloop}	43.419 ± 4.823^*	9.458 ± 0.274	5.793 ± 0.281
P-value	0.0212	0.3782	0.2377
WT	10.625 ± 1.806	7.957 ± 0.109	4.292 ± 0.201
Gαq^+/−	20.574 ± 3.228^*	8.076 ± 0.121	4.569 ± 0.174
P-value	0.0128	0.481	0.3007
WT	25.213 ± 2.994	8.097 ± 0.172	8.267 ± 0.379
CASR^+/−	40.443 ± 4.926^*	8.551 ± 0.144	8.244 ± 0.272
P-value	0.0302	0.0547	0.9607

CASR, calcium sensing receptor; PTH, parathyroid hormone; WT, wild type.

Values represent mean ± s.e.m. from more than six individual mice per group.

Significant difference between WT and Gαq^+/− or Tg^{PTHp–Gqloop} or CASR^+/− group mice at P < 0.05. The serum of WT and Gαq^+/− or Tg^{PTHp–Gqloop} was obtained from 8-week-old mice, and the serum of WT and CASR^+/− was obtained from 6-week-old mice.