Fig. 3.
Inhibition of monoamine oxidase A (MAO-A) does not elicit mitogenic effects of monoamines on E-PZ cells. Proliferation is measured in quadruplicate for each treatment by the sulforhodamine B assay. Standard deviation is calculated for each sample. Cells treated with 5-hydroxytryptamine (5-HT, or serotonin) and norepinephrine (NE) alone show similar growth rates as control cells. In the presence of clorgyline, no changes are observed in the growth rates of NE- or 5-HT- treated cells compared with control cells.