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MAO-A is down-regulated by androgen. Western blotting analysis shows MAO-A expression is significantly decreased in cells treated with clorgyline and androgen compared with control, and Casodex restores the MAO-A level to that of the control. GAPDH levels are determined as an internal control for experimental variations. The treatment conditions are shown on top of each lane. MAO-A, monoamine oxidase A; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.
