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. Author manuscript; available in PMC: 2009 Oct 12.
Published in final edited form as: Cancer Res. 2008 Sep 15;68(18):7352–7361. doi: 10.1158/0008-5472.CAN-07-6311

Figure 5. Expression of KIAA0358 in isolation can prevent apoptosis and suppress caspase-8 activity in SK-N-SH cells.

Figure 5

A. RT-PCR of IG20-SVs from stable cells expressing control vector (pEYFP-C1) or YFP-KIAA0358-Mut and infected with Mid-shRNA for five days. B. Mitochondrial depolarization assay. SK-N-SH cells were stained with DiIC to determine spontaneous apoptosis. Data shown are representative of three independent experiments (**P<0.01 vs SCR, ## P<0.01 vs Mid+pEYFP-C1). The data were collected from YFP and GFP double-positive cells only. C. Western blot showing caspase-8 activity. Cell lysates were subjected to western blot analysis of caspase-8. The data shown are representative of three individual experiments.