FIG. 4.

Pseudotype infectivity for wt and A226V CHIKV envelopes in mammalian cells. Equal amounts (normalized by p24 ELISA) of pseudotypes bearing CHIKV envelope wt or 226V mutant were titrated in parallel in different cell types. GFP titer was determined by flow cytometry. Each pseudotype was tested in triplicate for each cell type and error bars represent standard deviations (SDs). Differences in viral titers were analyzed by pairwise t-tests. Diamond indicates P > 0.3.