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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: J Comb Chem. 2009 Sep–Oct;11(5):875–879. doi: 10.1021/cc900057n

Table 4.

In silico parameters for gauging oral availability/drug-likeness

Mean St. Dev. Range
Clog P 5.1 1.9 0.6 – 8.0
Mol. Weight 317 53 227–433
H-Bond Acceptors 2.0 0.9 0 – 4
H-Bond Donors 0.8 0.8 0 – 3
Rotatable Bonds 4.1 1.1 2 – 6