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The effect of folate pre-incubation on DNA-NTs internalization as analyzed flow cytometry. (I) cells without any treatment; (II) cells incubated with folate-saturated medium for 1 hour; (III) cells incubated with folate-saturated medium for 1 hour and then with folate-functionalized DNA-NTs for 1 hour; (IV) cells incubated with folate-functionalized DNA-NTs for 1 hour.
