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Postnatal Lgl1+/- mice display increased expression of IL-4 and IL-13 mRNA. IL-4 and IL-13 mRNA was quantified in mRNA isolated from total lungs of Lgl1+/+ and Lgl1+/- mice by quantitative real-time RT PCR (N ≥ 4). A. Lgl1+/- display significantly elevated IL-4 levels at PN7 and PN14 compared to wild type controls (p ≤ 0.05). B. Lgl1+/- mice display significantly elevated levels of IL-13 at PN7 compared to wild type controls (p ≤ 0.05).
