Table 1.
Summary of subgroup characteristics in 1662 patients
| Variables (%) | Triple negative | ERBB2+ | HR+/ERBB2- | P value |
|---|---|---|---|---|
| n = 321 | n = 444 | n = 897 | ||
Mean age at diagnosis (year,  ± SD) |
52.02 ± 10.49 | 52.12 ± 9.99 | 53.16 ± 11.56 | 0.416 |
| Tumor size | ||||
| ≤ 2 cm | 139 (43.30) | 148 (33.33) | 439 (48.94) | < 0.001 |
| >2 cm | 182 (56.70) | 296 (66.67) | 458 (51.06) | |
| Number of ALNs involved | ||||
| 0 | 190 (59.19) | 233 (52.48) | 538 (59.98) | |
| 1-3 | 72 (22.43) | 107 (24.10) | 214 (23.86) | 0.020 |
| ≥ 4 | 59 (18.38) | 104 (23.42) | 145 (16.16) | |
| Histological grade | ||||
| I/II | 151(61.56) | 237 (74.29) | 499 (81.80) | 0.002 |
| III | 60 (28.44) | 82 (25.71) | 111 (18.20) | |
| Not known | 110 | 126 | 287 | |
| Systemic treatment | ||||
| Yes | 302 (94.08) | 426 (95.95) | 852 (94.98) | 0.494 |
| No | 19 (5.92) | 18 (4.05) | 45 (5.02) | |
| All relapse | ||||
| Yes | 51 (15.79) | 65 (14.64) | 79 (8.81) | < 0.001 |
| No | 270 (84.11) | 379 (85.36) | 818 (91.19) | |
| Locoregional relapse | ||||
| Yes | 25 (7.79) | 35 (7.79) | 35 (3.90) | 0.003 |
| No | 296 (92.21) | 409 (92.12) | 862 (96.10) | |
| Mean TTE (years) | 2.19 | 2.03 | 2.02 | ------ |
| Visceral relapse | ||||
| Yes | 15 (4.67) | 25 (5.63) | 23 (2.56) | 0.014 |
| No | 306 (95.33) | 419 (94.37) | 874 (97.44) | |
| Mean TTE (years) | 1.64 | 2.02 | 2.49 | ------ |
| Bone relapse | ||||
| Yes | 12 (3.74) | 7 (1.58) | 16 (1.78) | 0.074 |
| No | 309 (96.26) | 437 (98.42) | 881 (98.22) | |
| Mean TTE (years) | 3.04 | 2.24 | 2.57 | ------ |
Abbreviations: HR = hormone receptor; SD = standard deviation; ALNs = axillary lymph nodes; TTE = time to event