Table 2.
Cox proportional hazards regression analysis of RFS for locoregional, bone and visceral relapse in 1662 breast cancer patients
| Subgroup* | Univariate Cox model, HRs (95% CI) | P value | Multivariate Cox model, HRs (95% CI) | P value |
|---|---|---|---|---|
| Locoregional RFS | ||||
| ERBB2+ | 1.018(0.609-1.700) | 0.947 | 0.686(0.375-1.254) | 0.221 |
| HR+/ERBB2- | 0.522(0.312-0.873) | 0.013 | 0.521(0.293-0.927) | 0.027 |
| Visceral RFS | ||||
| ERBB2+ | 1.203(0.634-2.281) | 0.572 | 0.952(0.479-1.893) | 0.889 |
| HR+/ERBB2- | 0.568(0.296-1.090) | 0.089 | 0.339(0.158-0.724) | 0.005 |
| Bone RFS | ||||
| ERBB2+ | 0.468(0.183-1.198) | 0.113 | 0.384(0.148-0.991) | 0.048 |
| HR+/ERBB2- | 0.553(0.259-1.178) | 0.124 | 0.479(0.224-1.025) | 0.058 |
*Triple negative category was used as the reference group.
Abbreviations: RFS = relapse-free survival; HRs = hazard ratios; CI = confidence interval; HR = hormone receptor