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. Author manuscript; available in PMC: 2010 Nov 10.
Published in final edited form as: Neuroscience. 2009 Jul 30;163(4):991–1001. doi: 10.1016/j.neuroscience.2009.07.055

Figure 2.

Figure 2

Early life experience programs levels of neuronal tph2 mRNA expression, and tph2 mRNA responses to social defeat, in adult midbrain serotonergic neurons. A) Mean tph2 mRNA expression levels in MS15, AFR, and MS180 rats, regardless of adult experience, based on the mean expression levels in 47 subdivisions of the DR. B) Mean tph2 mRNA expression levels in adult rats exposed to a novel cage (control) or social defeat, regardless of early life experience, based on the mean expression levels in 47 subdivisions of the DR. C) Mean tph2 mRNA expression levels in MS15, AFR, and MS180 rats, exposed to a novel cage (control, left) or social defeat (right) as adults. Tph2 mRNA expression was measured 4 h following exposure to a novel cage control condition or to social defeat. +P < 0.05, ++P < 0.01 comparison of MS15 and AFR groups. *P < 0.05, ***P < 0.001, comparison of MS15 and MS180 groups. aP < 0.05, comparison of AFR and MS180 groups.