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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Neurobiol Dis. 2009 Aug 5;36(2):352–360. doi: 10.1016/j.nbd.2009.07.032

Figure 1. Time-of-day determines cardiac arrest survival.

Figure 1

Cardiac arrest reduced survival in normothermic mice that underwent CA/CPR during the Mid-Light period. Eighty-four percent of mice in the hypothermic groups survived CA/CPR. Among the normothermic groups, mice in the Light→Dark transition group and the Mid-Dark group survived at 76.9% and 75%, respectively. In contrast, only 33% of mice that underwent CA/CPR during the light period (Mid-Light group) survived to day 7 post-reperfusion. Thus, timing of CA/CPR significantly altered survival (Kaplan-Meier Survival Analysis; χ2=10.19, p<0.05). *Significantly different from all other groups at p<0.05.