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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Cell Signal. 2009 Aug 23;21(12):1874–1884. doi: 10.1016/j.cellsig.2009.08.003

Figure 8.

Figure 8

Effect of Mx1Cre-mediated conditional knock out of PPARγ on ROSI-induced neointima. Trichrome (panel A) and anti-αSMA (panel B) staining of a pIpC-treated Mx1Cre mouse carotid three weeks after treatment with 2.5 μM ROSI. Trichorme (panel C) and anti-αSMA (panel D) staining of a carotid from a pIpC-induced PPARγfl/− mouse. Trichorme (panel E) and anti-αSMA (panel F) staining of a carotid from a non-pIpC-induced Mx1CreXPPARγfl/− mouse carotid. Note the anti-αSMA positive neointimal cells inside the IEL. Trichorme (panel G) and anti-αSMA (panel H) staining of an pIpC-induced ΔPPARγ mouse three weeks after ROSI treatment. Note the complete lack of αSMA staining inside the IEL. Calibartion bars are 100 μm.