Table 3.
Confirmation of the presence of homologous repeat units in ABC1 and ABC2 proteins using four different programs
| ABC type | TMSsa | Protein 1 (organism) | Protein accessionb | TMSsa | Protein 2 (organism) | Protein accessionb | E valuec (LALIGN) | E valuec (GGSEARCH) | E valuec (GLSEARCH) | E valuec (PairwiseStatSig) | E valuec (average) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ABC-1 | 1 + 2 | Clostridium leptum DSM 753 | ZP_02078939 | 3 + 4 | Colwellia psychrerythraea 34H | YP_267051 | 5.9 × e−6 | 2.5 × e−13 | 1.6 × e−14 | 5.2 × e−6 | 6.0 × e−10 |
| ABC-1 | 1 + 2 | Caulobacter crescentus CB15 | NP_419501 | 5 + 6 | Rhodoferax ferrireducens T118 | YP_523966 | 2.6 × e−6 | 5.4 × e−15 | 4.9 × e−15 | 7.9 × e−7 | 9.0 × e−11 |
| ABC-1 | 3 + 4 | Aeromonas hydrophila subsp. hydrophila ATCC 7966 | YP_855895 | 5 + 6 | Unknown homologue | ZP_01811308 | 1.4 × e−6 | 5.5 × e−13 | 2.7 × e−10 | 1.7 × e−6 | 4.0 × e−9 |
| ABC-2 | 1–3 | Streptomyces avermitilis MA-4680 | NP_825831 | 4–6 | Burkholderia sp. 383 | YP_368972 | 5.8 × e−6 | 2.0 × e−14 | 4.5 × e−12 | 2.0 × e−6 | 1.0 × e−9 |
aTMSs, the transmembrane α-helical segments compared
bProtein accession number in the NCBI protein database
cE values reflect the probability that the alignment occurred by chance