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. Author manuscript; available in PMC: 2010 Oct 15.
Published in final edited form as: Org Lett. 2009 Oct 15;11(20):4485–4487. doi: 10.1021/ol9018562

Scheme 1.

Scheme 1

Reverse prenylation of isatin 1 and conversion to 3-chloro-3-tert-prenyl oxindole 3.a

aCompound 2 was isolated by crystallization from ethyl acetate-hexane. Compound 3 was isolated by silica gel chromatography. See Supporting Information for experimental details.