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. 2009 Jul 15;37(16):5331–5342. doi: 10.1093/nar/gkp592

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© 2009 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Expression of Ly49H in B6 Ly49h^+/− NK cells and comparison to the stochastic mono-allelic expression model. (A) Expression of a theoretical Ly49 receptor expressed on 50% of NK cells based on the stochastic mono-allelic model in an inbred mouse strain. (B) The percentage of peripheral blood NK cells expressing Ly49H in B6.BXD8/B6 (Ly49h^+/−) mice and age-matched B6 (Ly49h^+/+) were determined by FACS. P-value was calculated according to the two-tailed unpaired t-test. (C) Allelic expression of Ly49H in a theoretical B6 mouse based on the expression of this receptor in B6.BXD8/B6 (Ly49h^+/−) mice. The dashed circle and brackets indicated predicted expression patterns. (D) Allelic expression of Ly49D on NK cells based on the single-cell RT–PCR results (Table 2) in B6/NOD F1 hybrid. Each chromosome is shown with a line, the alleles are shown with rectangle, arrows indicate transcription and cross shows the deleted allele.