Table 1. Amino acids implicated in mAb binding to CCR5 as determined using CCR5 point mutants.

Mutation of the indicated amino acids was reported to reduce mAb binding to CCR5 as determined by flow cytometry.

Antibody	Epitope	Reference(s)
2D7	Q170, K171, E172, W190	[25;27;33;34]
502	D2, Y3	[27]
519	D2, Y3, Q4	[27]
45501	K171, E172	[27]
45517	K171, E172	[27]
45523	K171, E172, D95	[27]
45529	Y184, S185, Q186, Y187, Q188, F189	[27]
45531	Y184, S185, Q186, Y187, Q188, F189	[27]
45533	K171, E172	[27]
45549	K171, E172	[27]
CTC2	S6, S7, Y10, D11	[27]
CTC5	D2	[27]
CTC8	Y10, D11, I12, N13	[27]
CTC9	D2, Y3	[27]
CTC12	S7, I9, Y10, D11	[27]
MC-6	K171, E172	[33]
MC-7	S7, P8, Y10, D11	[33]
MCR35.4	Y184, S185, Q186, Y187, Q188, F189	[27]
MCR40.3	Y184, S185, Q186, Y187, Q188, F189	[27]
PA8	N13, Y15	[25]
PA9	D2, Y3, Q4, S7, P8, N13, Y176, T177	[25]
PA10	D2, Y3, Q4, P8, N13, Y176, T177	[25]
PA11	Q4	[25]
PA12	Q4	[25]
PA14	D2, R168, Y176	[25]
RoAb12	K171, E172, W190	[34]
RoAb14	K171, E172, W190	[34]
RoAb18	K171, E172, W190	[34]