Table 5.

Cytotoxic activity of compounds isolated from Callicarpa americana ^a,^b

Compound Code	Cell Linec,d
	MCF-7	Lu1	Col2	LNCaP	hTERT-RPE1	HUVEC
10	-	2.4	2.3	4.1	1.9	1.8
11	3.9	8.7	9	4.5	1.9	9.8
13	2.8	2.9	-	3.3	-	-
15	3.5	3.7	-	3.3	-	4.1
16	2.7	2.6	-	2.5	-	1.2
41	-	>20	>20	>20	3.9	>20

^aCompounds 6, 8, 9, 12, 14, 45, 50, and 88 were inactive in the cell lines tested.

^bAdapted from [36].

^cCell lines: MCF-7 = breast cancer; Lu1 = lung cancer; Col2 = colon cancer; LNCaP = hormone-dependent prostate cancer; hTERT-RPE1 = human telomerase reverse-transcriptase retinal pigment epithelium; HUVEC = human umbilical vein epithelial cells.

^dED₅₀ values are given in μg/mL, and values <5 μg/mL are considered to be active.