Table 3.
Differentially expressed genes that are polymorphic in SHR and WKY in which all SHR lines (SHR-A3, SHR-B2, SHR-C and SHR/N) share the same allele and contrast with both WKY-Heid and WKY/N. Shaded gene symbols indicate those genes whose differential expression is determined in cis. The p value of the regression analysis relating inheritance of SHR alleles of these genes with level of gene expression in 10 F2 animals is also indicated.
| Gene symbol | Gene | Band | Position | Expression inheritance in cis (p value) |
|---|---|---|---|---|
| Ddt | D-dopachrome tautomerase | 20p12 | chr20:13,592,013-13,594,480 | 0.142 |
| Ela1 | elastase 1 | 7q36 | chr7:139,515,742-139,529,176 | 0.001 |
| Gsto1 | glutathione S-transferase omega 1 | 1q54 | chr1:253,493,290-253,503,274 | 0.140 |
| Gstt2 | glutathione S-transferase, theta 2 | 20p12 | chr20:13,221,934-13,225,575 | 0.010 |
| Mat2a | methionine adenosyltransferase II, alpha | 4q33 | chr4:105,984,423-105,989,953 | 0.892 |
| Ptprj | protein tyrosine phosphatase, type J | 3q24 | chr3:74,693,135-74,831,912 | 0.001 |
| Slc17a1 | solute carrier family 17A1 | 17p11 | chr17:48,343,283-48,351,209 | 0.515 |
| Ugt1a6 | UDP glycosyltransferase 1, A6 | 9q35 | chr9:87,226,279-87,284,238 | 0.122 |
| AA866432 | EST | 8q11 | chr8:11,151,250-11,151,733 | 0.007 |
| AA892189 | EST | 3p13 | chr3:10,972,364-10,972,822 | 0.583 |
| AA892388 | EST derived from death-associated kinase 2 | 8q24 | chr8:70,581,319-70,585,265 | 0.001 |