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. Author manuscript; available in PMC: 2009 Oct 13.
Published in final edited form as: Virology. 2007 May 9;366(1):126–136. doi: 10.1016/j.virol.2007.03.059

Fig. 1. Primary and secondary structure of the phosphatase domain of T4 Pnkp.

Fig. 1

The amino acid sequence of T4 Pnkp from amino acids 159 to 301 is aligned with that of the phosphatase domain of the ORF86 polypeptide encoded by Autographa californica nucleopolyhedrovirus (AcNPV). Positions of side chain identity/similarity are denoted by ^ below the aligned sequences. The secondary structure elements of T4 Pnkp are shown above the amino acid sequence with β strands as arrows and α helices as bars. The amino acids of Pnkp that were mutated previously to alanine are denoted by + (nonessential for activity) or ● (essential or important for 3′ phosphatase activity). The amino acids in Pnkp that were mutated singly to alanine in the present study are indicated by !.