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. Author manuscript; available in PMC: 2009 Oct 13.
Published in final edited form as: Virology. 2007 May 9;366(1):126–136. doi: 10.1016/j.virol.2007.03.059

Table IV.

Effect of Double-Alanine Mutations on 3′-Phosphatase Activity

Pnkp Mutant 3′ phosphatase
(% of WT)
5′ kinase
(% of WT)
N190A-M192A 18 67
M199A-Y200A 19 76
E195A-Y205A 22 39
R287A-Q295A 2 34
E292A-W294A 3 30
S298A-D300A 27 95