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dsRNA:TLR3 signaling complex. Mouse TLR3 ectodomains (green and cyan) form a dimer on the dsRNA (blue and red). The N glycans are shown (light green and light blue). (A) The N- and C-terminal binding sites. (B) Illustration of how the two C-terminal domains are brought together in the complex. Figures generated with PyMol (DeLano Scientific, San Carlos, CA)
