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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Biochim Biophys Acta. 2009 May 6;1787(7):835–840. doi: 10.1016/j.bbabio.2009.04.015

Table 1.

Common HNO Donors Used in Biology

Donor Chemical
Structure		 Notes
Angeli's salt graphic file with name nihms127664t1.jpg - Fast release of HNO
- Nitrite is also formed
Piloty's acid graphic file with name nihms127664t2.jpg - Releases HNO only at high pH
Acyloxo nitroso "Blue compounds" graphic file with name nihms127664t3.jpg - Releases HNO upon cleavage of ester bond
- Rate of HNO release is controled by R substituent
- Reacts with thiols
IPA/NO graphic file with name nihms127664t4.jpg - Primary amine "NONOate"
- NO donor at lower pH
hetero-Diels-Alder cycloadduct graphic file with name nihms127664t5.jpg - Releases HNO upon photo activation
- Requires UV -A radiation (330 –380 nm)