Table 4.

Magnesium sulfate regimen variations between individual trials.

Study	Magnesium Regimen	Actual amount received (in the magnesium group)
BEAM	- 6 g bolus over 20–30 min then 2 g/h maintenance - maintenance stopped if delivery had not occurred in 12 h and was no longer considered imminent - infusion was resumed when delivery was deemed imminent again; if ≥ 6h from last infusion, another loading dose given	- 996/1096 (90.9%) received magnesium for ≥ 3 h - 82/1096 (7.5%) received magnesium < 3 h - 18/1096 (1.6%) did not receive magnesium - 27 (2.5%) received magnesium for other indications - magneisum dose median, (IQR): 31.5 (29.0–44.6) g
ACTOMgSO4	- 4 g bolus over 20 min then 1 g/h maintenance until birth or up to 24 h, whichever was first - treatment was not repeated	- 13/535 (2.4%) did not receive magnesium - 38/535 (7.1%) received partial loading dose only - 33/535 (6.2%) received full loading dose only - 381/535 (71.2%) received full loading + partial maintenance - 70/535 (13.1%) received full loading + full maintenance dose - 4 (0.7%) received magnesium for clinical reasons after enrollment - magnesium dose, median (IQR): 6.5 (4.5–14) g
PREMAG	- 4 g bolus over 30 minutes	- 20/286 (7.0%) did not receive magnesium - 7/286 (2.4%) received partial dose only - 259/286 (90.6%) received full dose 0 received magnesium for other indications
Magpie	- IV: 4 g bolus over 1–15 min then 1 g/h for 24 h - IM: 4 g IV bolus combined with 10 g IM, given as 5 g into each buttock, followed by 5 g Q 4 h for 24 h	- 4% did not receive magnesium - magnesium dose, median (IQR): 18 (9–29) g* - time to delivery, median (IQR): 12 (4–46) h*
MagNET	Preventive arm (P): 4 g bolus Tocolytic arm (T): 4 g bolus then 2–3 g/h	Did not report

^*Estimate – uncertain from published data, g=gram, h=hour, IV=intravenous, IM=intramuscular