Table 1.
Variable | Standard Use | Off-Label Use | ||||
---|---|---|---|---|---|---|
Bare-Metal Stent (N = 1748) | Drug-Eluting Stent (N = 1381) | P Value | Bare-Metal Stent (N = 2110) | Drug-Eluting Stent (N = 1312) | P Value | |
Mean age (yr) | 62.6 | 63.7 | 0.02 | 63.4 | 63.4 | 0.80 |
Female sex (%) | 37.3 | 33.1 | 0.01 | 33.3 | 31.2 | 0.19 |
Race or ethnic group (%)† | 0.009 | <0.001 | ||||
White | 79.2 | 74.5 | 82.7 | 76.4 | ||
Black | 11.1 | 15.2 | 8.9 | 15.4 | ||
Hispanic | 5.7 | 6.3 | 5.2 | 5.7 | ||
Asian | 3.8 | 3.4 | 3.1 | 2.3 | ||
Other | 0.2 | 0.6 | 0.1 | 0.2 | ||
Smoking history (%) | <0.001 | 0.71 | ||||
Never | 31.7 | 34.2 | 32.1 | 33.3 | ||
Current | 29.8 | 23.4 | 25.3 | 25.5 | ||
Former | 38.6 | 42.4 | 42.6 | 41.2 | ||
Diabetes (%) | 26.0 | 32.8 | <0.001 | 27.1 | 35.4 | <0.001 |
Hypertension (%) | 64.4 | 78.1 | <0.001 | 64.6 | 78.1 | <0.001 |
Renal disease (%) | 4.3 | 8.3 | <0.001 | 5.2 | 9.4 | <0.001 |
Peripheral vascular disease (%) | 6.0 | 6.9 | 0.31 | 8.5 | 9.7 | 0.24 |
Cerebrovascular disease (%) | 5.8 | 6.4 | 0.50 | 6.4 | 7.9 | 0.18 |
Previous PCI (%) | 18.2 | 27.3 | <0.001 | 27.7 | 39.0 | <0.001 |
Previous CABG (%) | 7.5 | 11.7 | <0.001 | 22.5 | 24.6 | 0.17 |
Previous myocardial infarction (%) | 28.8 | 20.9 | <0.001 | 33.1 | 27.1 | <0.001 |
Previous brachytherapy (%)‡ | 0.3 | 0.9 | 0.25 | 0.9 | 1.9 | 0.08 |
Congestive heart failure (%) | 8.2 | 8.3 | 0.90 | 11.0 | 9.9 | 0.38 |
Mean left ventricular ejection fraction (%) | 55.0 | 54.1 | 0.12 | 51.1 | 51.1 | 0.80 |
No. of diseased vessels (%) | <0.001 | <0.001 | ||||
0 | 0 | 0.1 | 0.6 | 0.5 | ||
1 | 48.0 | 41.3 | 38.1 | 31.9 | ||
2 | 33.8 | 32.4 | 31.1 | 30.9 | ||
3 | 18.1 | 26.1 | 30.2 | 36.7 | ||
Primary indication (%) | ||||||
Acute myocardial infarction | 25.4 | 25.3 | 0.98 | 31.5 | 30.2 | 0.42 |
Unstable angina | 42.8 | 36.2 | <0.001 | 40.8 | 31.7 | <0.001 |
Stable angina | 22.1 | 20.1 | 0.20 | 18.5 | 21.3 | 0.04 |
Ischemia | 5.6 | 12.8 | <0.001 | 5.5 | 12.7 | <0.001 |
Other | 4.1 | 5.6 | 0.07 | 3.7 | 4.1 | 0.54 |
CABG denotes coronary artery bypass grafting, and PCI percutaneous coronary intervention.
Race and ethnic group were self-reported.
Data were not available for waves 1 and 2.