Table 1.
Prevalence of antibodies to P. jirovecii recombinant Msg fragments in Cameroonian serum samples
| ELISA-positive (% of total samples)a |
||||
|---|---|---|---|---|
| Patient group | at least 1 fragmentb | MsgA1 | MsgB | MsgC1 |
| Totalc | 82 (286/349) | 60 (210/349) | 49 (171/349) | 55 (192/349) |
| JTH + EBC | 82 (201/245) | 60 (146/245) | 43 (102/245) | 55 (134/245) |
| EC | 81 (84/104) | 52 (54/104) | 50 (52/104) | 58 (60/104) |
a
With ELISA scores > geometric mean. All samples with ELISA scores >geometric mean (the nth root of a product of all mean OD values; n = number of samples) for the specific Msg fragment antigen were considered positive and therefore indicative of exposure to Pneumocystis.
b
Sera that reacted higher than the geometric means of one or more recombinant Msg fragment were considered positive for anti-P. jirovecii Msg antibodies.
c
All serum samples analyzed in this study (JTH + EBC + EC).