Table 3.
Reactivity to recombinant P. jirovecii Msg fragments of serum samples from total and HIV+ patients with diagnosed respiratory diseasea at the Etoug-Ebe Baptist Health Center (EBC) and the Jamot Tuberculosis Hospital (JTH) compared to patients at the Espoir HIV Clinic (EC) (geometric mean [95% confidence level]). The geometric mean is used because the data are log transformed
| % seropositiveb | MsgA1 | MsgB | MsgC1 | |
|---|---|---|---|---|
| Total in study (n = 34) | 82 (28/34) | |||
| HIV- (n = 4) | 75 (3/4) | |||
| HIV+(n = 30) | 90 (27/30) | |||
| HIV+ | ||||
| EBC + JTH (n = 13) | 92 (12/13) | 49 [19.9 - 120.8] | 5.8 [2.8 - 12.2] | 19.1 [9.7 - 37.3] |
| Espoir HIV Clinc (n = 17) | 88 (15/17) | 4.8 [2.1 - 10.8] | 5.4 [3.5 - 8.5] | 12.4 [8.8 - 17.3] |
| P | 0.0007 | 1.000 | 0.0753 | |
a
Tuberculosis or pneumonia.
b
Sera that reacted higher than the geometric means of one or more recombinant Msg fragment were considered positive for anti-P. jirovecii Msg antibodies.
c
Significance determined by the Mann-Whitney unpaired t-test. Bolded number indicates the difference is statistically significant.