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Characteristics of mammalian small RNAs
| Class | Length (nucleotides) | Synthesis | Function |
|---|---|---|---|
| miRNA | 21–23 | DICER-dependent | Regulation of translation and stability of target mRNAs |
| siRNA | 21–23 | DICER-dependent | Transposon suppression and pseudogene regulation of founding source mRNAs |
| piRNA | 24–31 | DICER-independent feed-forward amplification loop | Transposon regulation and unknown functions |
