Table 1.
Demographic characteristics and illness severity ratings at baseline for patients in large-scale, double-blind, placebo-controlled studies of modafinil
| Obstructive sleep apnea studies n = 446a | Shift work disorder studies n = 455a | Narcolepsy studies n = 530a | |
|---|---|---|---|
| Mean (SD) age, yr | 49.7 (9.4) | 39.5 (9.2) | 41.8 (13.3) |
| Gender, n (%) | |||
| Male | 340 (76) | 243 (53) | 239 (45) |
| Female | 106 (24) | 212 (47) | 291 (55) |
| Race, n (%) | |||
| White | 396 (89) | 321 (71) | 434 (82) |
| Black | 29 (7) | 99 (22) | 77 (15) |
| Other | 21 (4) | 34 (7) | 19 (4) |
| CGI-S rating | |||
| Not recorded | 43 (10) | 0 (0) | 0 (0) |
| Normal, mildly, or slightly ill | 121 (27) | 0 (0) | 91 (17) |
| Moderately ill | 199 (45) | 280 (62) | 237 (45) |
| Markedly, severely, or extremely ill | 83 (19) | 175 (38) | 202 (38) |
a
Patients receiving one dose of study medication (modafinil or placebo) who had at least one post-baseline follow-up. Adapted from Schwartz 2005.
Abbreviations: SD, standard deviation; CGI-S, clinical global impression of severity.