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Naturally occurring cyclodextrins. From left to right: alpha, beta, and gamma. Sites of modification for the creation of sugammadex are the peripheral 6th carbon hydroxyl groups on the gamma cyclodextrin. Reproduced with permission from Welliver M. 2007. Update for nurse anesthetists. Part 3. Cyclodextrin introduction to anesthesia practice: form, function, and application. AANA J, 75:289–96. Copyright© 2007 American Association of Nurse Anesthetists.
